publications

ANGION PUBLICATIONS
RELEVANT SCIENTIFIC LITERATURE

Fibrosis

Role of receptor tyrosine kinase signaling in renal fibrosis (Liu & Zhuang) June 2016 – International Journal of Molecular Science
Drug and targets in fibrosis (Li, et al) November 2017 – Frontiers in Pharmacology

ROCK Inhibition

The Rho Kinases: Critical Mediators of Multiple Profibrotic Processes and Rational Targets for New Therapies for Pulmonary Fibrosis (Knipe, et al) January 2015 – Pharmacological Reviews
ROCK and Rho: Promising therapeutic targets to ameliorate pulmonary fibrosis (Riches, et al) April 2015 – The American Journal of Pathology

CYP11B2 Inhibition

HGF/c-Met Pathway

Combination therapy with hepatocyte growth factor and oseltamivir confers enhanced protections against influenza viral pneumonia (Narasaraju, et al) June 2014 – Current Molecular Medicine
Hepatocyte growth factor in lung repair and pulmonary fibrosis (Panganiban & Day) July 2014 – American Journal of Respiratory and Critical Care Medicine
Lung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor/c-Met signaling (Ito, et al) July 2014 – American Journal of Respiratory and Critical Care Medicine
Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury (Zhou, et al) September 2013 – Kidney International
The discovery of Hepatocyte Growth Factor (HGF) and its significance for cell biology, life sciences and clinical medicine (Nakamura & Mizuno) June 2010 – Proceedings of the Japan Academy. Series B Physical and Biological Sciences
Hepatocyte growth factor: From diagnosis to clinical applications (Funakoshi & Nakamura) January 2003 – Clinica Chimica Acta
Up-regulation of hepatocyte growth factor receptor: an amplification and targeting mechanism for hepatocyte growth factor action in acute renal failure (Liu, et al) February 1999 – Kidney International

Acute Kidney Injury

A Clinical Score to Predict Acute Renal Failure after Cardiac Surgery (Thakar et al 2005) January 2005 – Journal of the American Society of Nephrology
The Lifetime Health Burden of Delayed Graft Function in Kidney Transplant Recipients in the United States (Incerti, et al) June 2018 – MDM Policy & Practice
Delayed Graft Function: The AKI of Kidney Transplantation (Mannon) June 2018 – Nephron Clinical Practice
Improving the Supply and Quality of Deceased-Donor Organs for Transplantation (Tullus & Rabb) May 2018 – New England Journal of Medicine
Heart Disease and Stroke Statistics 2018 Update: A Report From the American Heart Association (Benjamin, et al) March 2018 – Circulation
Cardiac surgery-associated acute kidney injury: Risk factors, pathophysiology and treatment (Wang & Bellomo) November 2017 – Nature Reviews Nephrology
The Economic Consequences of Acute Kidney Injury (Silver & Chertow) April 2017 – Nephron: Clinical Practice
Acute Kidney Injury in the Era of the AKI E-Alert (Holmes, et al) December 2016 – The American Society of Nephrology
Acute kidney injury following cardiac surgery: Current understanding and future directions (O’Neal, et al) July 2016 – Critical Care
Delayed graft function and the risk of acute rejection in the modern era of kidney transplantation (Wu, et al) October 2015 – International Society of Nephrology
Hospital-acquired acute kidney injury and hospital readmission: A cohort study (Koulouridis, et al) February 2015 – American Journal of Kidney Diseaes
Acute kidney injury (Bellomo, et al) August 2012 – Lancet
Acute kidney injury: What’s the prognosis? (Murugan & Kellum) April 2011 – Nature Reviews Nephrology
Duration of acute kidney injury impacts long-term survival after cardiac surgery (Brown, et al) October 2010 – The Annals Thoracic Surgery
Acute kidney injury predicts outcomes of non-critically ill patients (Barrantes, et al) May 2009 – Mayo Clinic Proceedings
Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery (Hobson, et al) May 2009 – Circulation
Preoperative risk factors for the development of acute renal failure in cardiac surgery (Kochi, et al) March 2007 – Brazilian Journal of Cardiovascular Surgery
Incidence and outcomes in acute kidney injury: A comprehensive population-based study (Ali, et al) April 2007 – Journal of the American Society of Nephrology
Comparison of early renal function parameters for the prediction of 5-year graft survival after kidney transplantation (Schnuelle, et al) January 2007 – Nephrology Dialysis Transplantation

Acute Lung Injury

Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment (Johnson & Mathay) August 2010 – Journal of Aerosol Medicine & Pulmonary Drug Delivery
Acute respiratory distress syndrome: epidemiology and management approaches (Walkey, et al) July 2012 – Clinical Epidemiology
Cost and Healthcare Utilization in ARDS – Different from Other Critical Illness? (Bice, et al) August 2013 – Seminars in Respiratory and Critical Care Medicine

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